Researchers at Northwestern Medicine have identified that uterine serous carcinoma (USC) tumors in Black patients exhibit more aggressive and immunosuppressive traits compared to those in white patients, as revealed in a study published on August 12 in Proceedings of the National Academy of Sciences.
USC, a rare and aggressive form of endometrial cancer, accounts for up to 10% of all primary endometrial cancer cases, according to the Foundation for Women’s Cancer. The five-year survival rate for advanced cases hovers around 30%.
Black women are disproportionately affected by USC, with previous studies showing distinct cancer driver mutations in tumors from Black patients compared to white patients.
